一種新型內(nèi)源性凝血酶潛能(ETP)檢測(cè)方法能夠用于測(cè)定凝血酶的活性，現(xiàn)在已經(jīng)可以用于科研研究。

這種方法是基于這樣的假設(shè)：血漿或全血中生成的凝血酶代表的是促凝血和抗凝血物質(zhì)的活性、濃度的總和。ETP檢測(cè)方法最初是開(kāi)發(fā)用于測(cè)定血小板含量較低血漿中凝血酶生成的方法，現(xiàn)在可以在大學(xué)醫(yī)院以及Dade Behring公司的標(biāo)準(zhǔn)實(shí)驗(yàn)室中用于科研目的。

Dade Behring公司主席、總裁兼首席執(zhí)行官Jim Reid-Anderson說(shuō)：“ETP具有變成凝結(jié)試驗(yàn)標(biāo)準(zhǔn)參數(shù)的可能，我們十分自信，研究試驗(yàn)將為我們把這項(xiàng)檢測(cè)完全進(jìn)行商品化操作，提供所必須的信息。”

他補(bǔ)充說(shuō)：“我們十分高興能夠提供這項(xiàng)革新性新型檢測(cè)方法，這種檢測(cè)具有廣泛的臨床應(yīng)用前景，能夠?yàn)榕R床醫(yī)生更好地評(píng)估凝血與出血危險(xiǎn)，從而更加有效地治療患者。”
 
Research-Use Thrombin Assay
 
A new endogenous thrombin potential (ETP) assay for the measurement of thrombin activity is now available for research studies.

The assay is based on the assumption that thrombin generation in plasma or whole blood reflects the sum of the activities and concentrations of procoagulant and anticoagulant substances. The ETP assay was originally developed for the measurement of thrombin generation in platelet-poor plasma and is now being offered for research use only to university hospitals and reference centers by Dade Behring (Deerfield, IL, USA).

“ETP has the potential to become a standard parameter in coagulation, and we are confident that the research studies will provide the necessary information that we need to bring the assay to full commercialization,” observed Jim Reid-Anderson, chairman, president, and CEO of Dade Behring.

“We are pleased to be able to provide an innovative new assay with the possibility of broad clinical applications that could allow physicians to better assess thrombotic and bleeding risk and treat patients more effectively,” he added.